Compile Data Set for Download or QSAR
Found 31 of ic50 data for polymerid = 1359
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PNMTMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potencyMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50240934(3-(hydroxymethyl)-N-(3,3,3-trifluoropropyl)-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of PNMTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58M4HPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028902(7,8-dichloro-2-[2-(7,8-dichloro-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029108(6,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline | ...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028908(7,8-dichloro-2-[4-(7,8-dichloro-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029107(8-Chloro-1,2,3,4-tetrahydro-isoquinoline | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029102(7-Chloro-1,2,3,4-tetrahydro-isoquinoline | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potencyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029101(5,6,7,8-Tetrachloro-1,2,3,4-tetrahydro-isoquinolin...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029099(5,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline | ...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potencyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028903(7,8-dichloro-2-[3-(7,8-dichloro-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029106(2,3-Dichloro-benzylamine | CHEMBL13165)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028910(7,8-dichloro-2-[6-(7,8-dichloro-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028901(7,8-Dichloro-2-ethyl-1,2,3,4-tetrahydro-isoquinoli...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028914(7,8-dichloro-2-[7-(7,8-dichloro-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028911(7,8-dichloro-2-[8-(7,8-dichloro-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028909(2-(7,8-Dichloro-3,4-dihydro-1H-isoquinolin-2-yl)-e...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028913(7,8-Dichloro-2-propyl-1,2,3,4-tetrahydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028912(2-Benzyl-7,8-dichloro-1,2,3,4-tetrahydro-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM12584((3-chlorophenyl)methanamine | 1-(3-CHLOROPHENYL)ME...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028906(7,8-dichloro-2-[5-(7,8-dichloro-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029104(2-Chloro-benzylamine | CHEMBL12712)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029105(2-(3,4,-dichlorophenyl)ethylamine | 2-(3,4-Dichlor...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028905(7,8-Dichloro-2-(6-phenyl-hexyl)-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029103(2-(3-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL14...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028907(6-(7,8-Dichloro-3,4-dihydro-1H-isoquinolin-2-yl)-h...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50506000(CHEMBL4445337)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6 tagged PNMT using norepinephrine as substrate preincubated for 10 mins in presence of AdoMet followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD43VSPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50028904(2-(6-Bromo-hexyl)-7,8-dichloro-1,2,3,4-tetrahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ08VHPubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50029100(2-(4-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL35...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47N5SPubMed